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The first museum hotel

Nestled in downtown Louisville on historic West Main Street, along Museum Row, 21c Museum Hotel is a multi-venue contemporary art museum, an award-winning 91-room boutique hotel, and home to acclaimed Proof on Main restaurant. Stay with us and the iconic Red Penguin

(UPDATED 7.29.21):21c continues to follow the latest CDC guidelines in the fight against Covid-19. With cases on the rise, we are asking all teammates, regardless of vaccination status, to wear a mask in all public spaces.  We are recommending all guests do as well. For the most up-to-date information about all of our cleanliness and wellness policies, designed with the safety of our teammates and guests in mind, click here.