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Bentonville
Located on the northeast corner of the Bentonville town square, 21c Museum Hotel Bentonville is a combination boutique hotel, contemporary art museum, cultural center and home to The Hive restaurant.
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Chicago
Located one block from the famed Magnificent Mile, 21c Chicago is steps away from the city’s best attractions. Book today and enjoy the hospitality that makes 21c a consistent winner in the Top Ten Chicago Hotels rankings.
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Cincinnati
21c Museum Hotel Cincinnati retains the historic character of the former Metropole Hotel while offering a blend of contemporary art, luxurious hospitality, a full-service spa and chef-driven cuisine - all in the heart of downtown Cincinnati.
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Durham
Standing tall and proud in the center of downtown, 21c Durham is a multi-venue contemporary art museum, a full service boutique hotel with luxurious guest rooms, and home to Counting House restaurant.
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Kansas City
Nestled between the Power & Light district and River Market in downtown Kansas City, 21c Museum Hotel will refresh your soul with contemporary art, comfort and culinary mastery from the historic Savoy.
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Lexington
Situated in the heart of historic downtown, 21c Museum Hotel Lexington is an 88-room boutique hotel, contemporary art museum, and home to Lockbox restaurant.
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Louisville
21c Louisville delivers a new kind of travel experience - a contemporary art museum, thoughtfully designed guest rooms and a first class bar & restaurant on-site. Located in the heart of Bourbon Country, your escape awaits.
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St. Louis
Located in the heart of downtown St. Louis, this 173-room boutique hotel houses a contemporary art museum, the Idol Wolf restaurant, the Good Press café, and the Locust Street Athletic and Swim Club, a full-service wellness center.