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21c Museum Hotels is proudly headquartered along historic West Main Street in Downtown Louisville, Kentucky.

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pr@21cHotels.com

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For 21c Bentonville reservations, call:
479.286.6500
> Book online

For 21c Chicago reservations, call:
312.660.6100
> Book online

For 21c Cincinnati reservations, call:
513.578.6600
> Book online

For 21c Durham reservations, call:
919.956.6700
> Book online

For 21c Kansas City reservations, call:
816.443.4200
> Book online

For 21c Lexington reservations, call:
859.899.6800
> Book online

For 21c Louisville reservations, call:
502.217.6300 or 1.877.217.6400
> Book online

For 21c St. Louis reservations, call:
314.940.2333
> Book online

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