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21c Museum Hotels is proudly headquartered along historic West Main Street in Downtown Louisville, Kentucky.

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Want to book a room?

For 21c Louisville reservations, call:
502.217.6300 or 1.877.217.6400
> Book online 

For 21c Cincinnati reservations, call:
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For 21c Bentonville reservations, call:
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For 21c Oklahoma City reservations, call:
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For 21c Nashville reservations, call:
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