Located on Main Street in the heart of downtown Lexington, 21c Museum Hotel blends contemporary art with a unique hotel experience, offering an inspiring space for culture, creativity, and comfort.
Rooms & Suites
Make yourself at home. With spacious high ceilings and large historic windows with downtown views, the guest rooms and suites offer a residential feel and comfortable respite after a long day of adventure.
Inspired by the ordered asymmetry of crystals, New York design studio SOFTLab has transformed the entry of the 1914 Fayette National Bank into an immersive installation that looks different from every angle
Inside Lockbox’s private dining space, The Safe, Lyons and Wilson’s contemporary ceramic tile installations featuring images of bullet casings reference aspects of cultural antiquity while addressing current social, economic, and political issues.
Our Lobby restaurant is temporarily closed for renovation. Rest assured, we’ve got Room Service available daily offering Breakfast and Dinner, and our Lobby Lounge open daily from 4pm.
WHAT'S ON
Meetings & Events
Looking for something spectacular? Our private event spaces play perfect host for all your wildest party-planning dreams. Corporate conferences, weddings, cocktail parties, and everything in between, let us lead the way.
Located on Main Street in the heart of downtown, 21c is the perfect base for exploring all that Lexington has to offer. From the Keeneland Race Course to The Kentucky Bourbon Trail, you’re just minutes away from it all.
