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One of a kind.

21c Museum Hotel Lexington is an 88-room boutique hotel, contemporary art museum, cultural center and home to Lockbox restaurant. Woven into the fabric of downtown Lexington, 21c welcomes both visitors and the local community to enjoy the curated exhibitions and cultural programming. Stay with us and the iconic Blue Penguin. 

(UPDATED 7.29.21):21c continues to follow the latest CDC guidelines in the fight against Covid-19. With cases on the rise, we are asking all teammates, regardless of vaccination status, to wear a mask in all public spaces.  We are recommending all guests do as well. For the most up-to-date information about all of our cleanliness and wellness policies, designed with the safety of our teammates and guests in mind, click here.