Looking for Louisville, KY hotels? Nestled in historic downtown Louisville, 21c Museum Hotel is a 91-room boutique Louisville hotel, contemporary art museum, award-winning restaurant and cultural civic center. Stay with us and the iconic Red Penguins, an iconic exhibition by the Cracking Art Group. As one of the most unique hotels in Louisville, KY, we pride ourselves on offering one-of-a-kind experiences for our guests who are visiting the area for business and leisure alike. Discover the plush amenities featured in our chic boutique hotel and enjoy a stay in one of our 91 luxurious guest rooms.
“Creatively balancing art and commerce, the hotel is a community crossroads that breathes new life into a rebounding urban corridor.”